CANCER TEST
STOMACH CANCER
SomArray Stomach
Information
Questions
Turn Around Time:
SomArray Stomach Basic: 9 business days*
SomArray Stomach Broad: 9 business days*
* If the sample needs to be enriched to ensure successful results, we will contact you
I Choose
SomArray Stomach Basic
With the SomArray Stomach Basic we focus on detecting the expression of the PD-L1 and CLDN18 proteins, as well as checking for HER2 amplification . We also test for microsatellite instability (MSI or MMR). The panel also offers a test for the presence of EBV.Consult your Oncologist for the best choice and personalization for you. There is the possibility of further personalization of the tests.
In case your sample is not already at Microdiagnostics archive, please contact us immediately so that we can arrange for its safe and rapid transport to our laboratory. You will also need to quickly and easily complete the Consent Form.
The number and type of mutations examined is updated through a dynamic process in accordance with current scientific research. It should therefore be recognized that there is a possibility that the list of genes on the order form may have changed (genes added or removed) during the analysis of the sample in the laboratory.
SomArray Stomach Broad
With SomArray Stomach Broad, in addition to the aforementioned 3 genes/proteins and testing for microsatellite instability (MSI or MMR) and EBV of Basic, 4 additional genes (NTRK1, 2, 3, FGFR2b) are added to the panel , to test for the presence of rearrangements and protein expression, providing an even more detailed and broad molecular profile of stomach cancer.
Consult your Oncologist for the best choice and personalization for you. There is the possibility of further personalization of the tests.
In case your sample is not already at Microdiagnostics archive, please contact us immediately so that we can arrange for its safe and rapid transport to our laboratory. You will also need to quickly and easily complete the Consent Form.
The number and type of mutations examined is updated through a dynamic process in accordance with current scientific research. It should therefore be recognized that there is a possibility that the list of genes on the order form may have changed (genes added or removed) during the analysis of the sample in the laboratory.
If you have been diagnosed with stomach cancer (diagnosis based on histology), you are likely to be eligible for molecular profiling of your cancer. This molecular test aims to detect whether your tumor has microsatellite instability (MSI/MMR) or protein expression abnormalities (PD-L1, HER2, CLDN18), which are closely associated with the cancer’s response to the treatment that will be chosen.
Based on the determination of the molecular profile, the Oncologist is given the opportunity to choose the optimal chemotherapy regimen, or immunotherapy, depending on the stage of the tumor.
Consult your Oncologist for the best option for you.
The tests are performed on the surgical specimen (paraffin cubes) or the biopsy material (paraffin cube) from which your histological examination was performed or on the aspiration material (FNAB, EBUS) from which your cytological examination was performed. In our fully integrated Laboratory, the pathologist selects the most appropriate & representative paraffin cube, ensuring that the most appropriate sample will be used for the tests. Qualitative and quantitative parameters are checked.
In case your sample is not already at Microdiagnostics archive, please contact us immediately so that we can arrange for its safe and rapid transport to our laboratory. You will also need to quickly and easily complete the Consent Form.
In our fully integrated Laboratory, we handle your sample in such a way as to minimize unnecessary waste and time:
- The paraffin cube is placed, if possible, once on the microtome for obtaining tissue sections, by experienced tissue technologists.
- Tissue sections are obtained sequentially in such a way as to ensure diagnosis and perform Immunohistochemistry if required.
- Ensuring preservation of tissue sections for further molecular testing.
- Pathologists perform microdissection to ensure the maximum amount of cancer cells possible, removing all other necrotic cells or normal tissue that could affect the validity of the results.
- The molecular biologist immediately processes the tissue in a fully controlled environment, using next-generation sequencing (NGS) or real-time polymerase chain reaction (Real-time PCR) to identify mutations in the genes of interest.
Frequently Asked Questions (FAQ)
If you have been diagnosed with stomach cancer (diagnosis based on histology), you are likely to be eligible for molecular profiling of your cancer. This molecular test aims to detect whether your tumor has microsatellite instability (MSI/MMR) or protein expression abnormalities (PD-L1, HER2, CLDN18), which are closely associated with the cancer’s response to the treatment that will be chosen.
Based on the determination of the molecular profile, the Oncologist is given the opportunity to choose the optimal chemotherapy regimen, or immunotherapy, depending on the stage of the tumor.
Consult your Oncologist for the best option for you.
The tests are performed on the surgical specimen (paraffin cubes) or the biopsy material (paraffin cube) from which your histological examination was performed or on the aspiration material (FNAB, EBUS) from which your cytological examination was performed. In our fully integrated Laboratory, the pathologist selects the most appropriate & representative paraffin cube, ensuring that the most appropriate sample will be used for the tests. Qualitative and quantitative parameters are checked.
In case your sample is not already at Microdiagnostics archive, please contact us immediately so that we can arrange for its safe and rapid transport to our laboratory. You will also need to quickly and easily complete the Consent Form.
Most of the time, the sample material we are called upon to handle is small because it has resulted from a minimally invasive method (needle biopsy, fluid aspiration, paraffin block with minimal material).
In our laboratory, Pathologists check in a timely manner whether the material to be examined is sufficient. If so, then a management algorithm is followed, with the aim of achieving the performance of multiple tests on the material (Immunohistochemistry, real-time PCR, NGS) in order to fully check the molecular profile of your tumor (proteins, genes, histological Grading).
In this case, and once sample enrichment manipulations have been exhausted, we contact your clinician to discuss alternative approaches in order to obtain the desired information to select the optimal treatment for you. Some examples:
- Performing an alternative test (e.g. Immunohistochemistry instead of PCR, or choosing Next Generation Sequencing (NGS))
- Performing Immunohistochemistry instead of FISH (Fluorescent In Situ Hybridization) and tubulin
- Possible blood sampling instead of tissue testing (liquid biopsy)
- Possible option to take a new biopsy or puncture
Contact us at 2310 23 22 72 and we will immediately arrange for your quick sample transfer to our laboratory.
Via bank card, bank deposit, or online bank deposit
One of the primary concerns of microDiagnostics’ Ltd is the protection of your personal data as well as the strict adherence to the conditions protecting your genetic material and medical results.
In full compliance with the General Data Protection Regulation (GDPR) we ensure that you are aware and conscious for any examination will be conducted and we do not announce results via phone calls.