SomArray Stomach

If you have been diagnosed with stomach cancer (diagnosis based on histological examination), it is possible that the indications for determining the molecular profile of cancer may be fulfilled. This molecular examination aims to detect whether the tumor exhibits instability in specific genes (MLH1, MSH2, MSH6, PMS2) or protein expression disorder (PD-L1, HER2), which seems to be closely related with pancreatic’s cancer response in the treatment which will be selected.

Based on the determination of the molecular profile, the oncologist is given the opportunity to choose the optimal chemotherapy regimen, or immunotherapy, depending on the stage of the tumor.

Consult your Oncologist for the best option for you.

The examination is performed on the biopsy material or surgical specimen (paraffin block) on which your histology examination has been conducted as well.

If your sample is not already in microDiagnostics Ltd files, contact us to arrange for safe and fast shipping to our laboratory.
You will also need to complete the Consent Form easily and quickly

At our vertically integrated Laboratory, we handle your sample in such a way as to minimize its unnecessary waste:

• The paraffin block is inserted if it is possible once in the microtome to obtain tissue sections by experienced histotechnologists.
• Tissue sections are sequentially acquired in such a way as to provide immunohistochemical stains if required.
• Ensure maintenance of tissue sections for further molecular testing.
• Pathologists perform microdissection, in order to ensure the highest possible amount of cancer cells, removing all other necrotic cells or normal tissue that could affect the validity of the results.
• Directly, the molecular biologist treats the tissue in a completely controlled environment with next-generation sequencing (NGS), or polymerase chain reaction of real-time (Real-time PCR) for the detection of mutations in genes of interest.

If you have been diagnosed with stomach cancer (diagnosis based on histological examination), it is possible that the indications for determining the molecular profile of cancer may be fulfilled. This molecular examination aims to detect whether the tumor exhibits instability in specific genes (MLH1, MSH2, MSH6, PMS2) or protein expression disorder (PD-L1, HER2), which seems to be closely related with pancreatic cancer response in the treatment which will be selected.

Based on the determination of the molecular profile, the oncologist is given the opportunity to choose the optimal chemotherapy regimen, or immunotherapy, depending on the stage of the tumor.

Consult your Oncologist for the best option for you.

The tests are performed on the surgical specimen (paraffin cubes) or the biopsy material (paraffin cube) from which your histological examination was performed or on the aspiration material (FNAB, EBUS) from which your cytological examination was performed. In our fully integrated Laboratory, the pathologist selects the most appropriate & representative paraffin cube, ensuring that the most appropriate sample will be used for the tests. Qualitative and quantitative parameters are checked.

In case your sample is not already at Microdiagnostics archive, please contact us immediately so that we can arrange for its safe and rapid transport to our laboratory. You will also need to quickly and easily complete the Consent Form.

Most of the time, the sample material we are called upon to handle is small because it has resulted from a minimally invasive method (needle biopsy, fluid aspiration, paraffin block with minimal material).

In our laboratory, Pathologists check in a timely manner whether the material to be examined is sufficient. If so, then a management algorithm is followed, with the aim of achieving the performance of multiple tests on the material (Immunohistochemistry, real-time PCR, NGS) in order to fully check the molecular profile of your tumor (proteins, genes, histological Grading).

In this case, and once sample enrichment manipulations have been exhausted, we contact your clinician to discuss alternative approaches in order to obtain the desired information to select the optimal treatment for you. Some examples:

• Performing an alternative test (e.g. Immunohistochemistry instead of PCR, or choosing Next Generation Sequencing (NGS))
• Performing Immunohistochemistry instead of FISH (Fluorescent In Situ Hybridization) and tubulin
• Possible blood sampling instead of tissue testing (liquid biopsy)
• Possible option to take a new biopsy or puncture

Contact us at 2310 23 22 72 and we will immediately arrange for your quick sample transfer to our laboratory.

Via bank card, bank deposit, or online bank deposit

One of the primary concerns of microDiagnostics’ Ltd is the protection of your personal data as well as the strict adherence to the conditions protecting your genetic material and medical results.

In full compliance with the General Data Protection Regulation (GDPR) we ensure that you are aware and conscious for any examination will be conducted and we do not announce results via phone calls.